FNA-based Molecular Testing of Thyroid Nodules: A Practical Update for Cytologists

 

Michiya Nishino, MD, PhD
Director of Head & Neck Pathology
Program Director of Cytopathology Fellowship
Associate Professor of Pathology
Harvard Medical School
Beth Israel Deaconess Medical Center
Boston, Massachusetts

 

Over the past decade, several molecular diagnostic tests have been developed for thyroid FNA biopsy samples. Tests currently marketed in the United States include Afirma GSC and Xpression Atlas (Veracyte), ThyroSeq (Sonic Healthcare USA), and ThyGeNEXT / ThyraMIR (Interpace Diagnostics). This webinar will highlight established and emerging roles of molecular testing in the clinical evaluation of thyroid nodules, provide a framework for understanding the different molecular approaches (i.e., genotyping, mRNA expression, microRNA expression) for risk-stratifying thyroid aspirates, and compare the strengths, limitations, and applications of the commercially available tests listed above.

Target Audience

This educational activity is designed for pathologists, cytopathologists, cytotechnologists, students and other members of the cytopathology community.

Learning Objectives

  • Explain the purpose of molecular testing for thyroid FNA samples
  • Develop a framework for understanding how molecular testing is performed on thyroid FNA specimens
  • Compare the design and performance of the three major molecular testing platforms that are currently marketed for thyroid FNA specimens
Course summary
Available credit: 
  • 2.00 AMA PRA Category 1 Credit™
  • 1.00 California Credits
  • 2.00 CMLE
  • 2.00 Florida Credits
  • 2.00 Participant
Course opens: 
10/24/2023
Course expires: 
10/23/2026
Cost:
$105.00

Presenter(s): Michiya Nishino, MD, PhD

DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS
The faculty, committee members, Executive Board and staff who are in position to control the content of this activity are required to disclose to the ASC and to learners any financial relationships that have occurred within the last 24 months with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. The ASC has reviewed the disclosures and mitigated all relevant financial relationships.

The following individuals have reported financial relationships:
Oscar Lin MD PhD: Consultant – Hologic and Jansen
Liron Pantanowitz MD: Consultant – Hamamatsu, Advisory Board for Ibex
Martha B Pitman MD FIAC: Consultant – Adenocyte, LLC
Donna K. Russell MEd CT(ASCP) HT(ASCP): Advisory Board – Hologic Scientific
Christopher J. VandenBussche MD PhD: Ad hoc advisory board panel and Consultant – Roche

The following individuals have reported no relevant financial relationships:
Susan A. Alperstein, MS, CT(ASCP), Donna Armyalagos, BA, CT(ASCP), Cheryl K. Arnott, SCT(ASCP), Kristen A. Atkins, MD, Khalid Amin, MD, Guliz A. Barkan, MD, Christine N. Booth, MD, Barbara A. Centeno, MD, Bonnie Choy, MD, Deborah J. Chute, MD, Amy C. Clayton, MD, Jacqueline M. Cuda, BS, SCT(ASCP), Kara L. Hansing, MEd, SCT(ASCP)CM, Elizabeth M. Jacobi, MD, Jennifer B. Kernodle-Zimmer, BS, SCT(ASCP), Sara E. Monaco, MD, Caleigh-Shea Murphy, Gabriela M. Oprea-Ilies, MD, Maria Luisa C. Policarpio-Nicolas, MD, Sinchita Roy-Chowdhuri, MD, PhD, Momin T. Siddiqui, MD, FIAC, Jose Victor Scarpa Carniello, MD, Sheila Segura, MD, Paul N. Staats, MD

The ASC staff associated with the development of content for this activity reported no relevant financial relationships.

Presenters:
Dr. Nishino has received consultation/contractor fees from EBIX/Oakstone CME, unrelated to the content of this presentation.

ACCREDITATION AND DESIGNATION STATEMENTS

Continuing Medical Education (CME) Statement
The American Society of Cytopathology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.  The American Society of Cytopathology designates this enduring educational activity for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

American Board of Pathology Continuing Certification (CC)
This product can help fulfill the CME requirements mandated by the American Board of Pathology Continuing Certification (CC) process.  Earn up to 2.0 Credit Hours.

Continuing Medical Laboratory Education (CMLE)
The ASC designates this activity for a maximum of 2.0 Continuing Medical Laboratory Education (CMLE) credit hours for non-physicians.  The CMLE credit hours meet the continuing education requirements for the ASCP Board of Registry Certification Maintenance Program. Participants should claim only the credit commensurate with the extent of their participation in the activity.

Cytotechnologists with Licenses in Florida and California
This program is approved for 2 continuing education credits in the State of Florida and 1 in the State of California. The credit on each link is good for three years from the live presentation date.

Available Credit

  • 2.00 AMA PRA Category 1 Credit™
  • 1.00 California Credits
  • 2.00 CMLE
  • 2.00 Florida Credits
  • 2.00 Participant

Price

Cost:
$105.00
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